Assessment of Periodontal Disease Indices in Breast Cancer Patients: A Case-Control Study

¹Oncologist, Specialized in Clinical Oncology, Cytology and Histopathology, Department of Pathological Anatomy, Medical School, University of Athens, Athens, Greece

²Resident in Maxillofacial and Oral Surgery, 401 General Military Hospitals of Athens, Athens, Greece

³Department of Dermatology, Rio University Hospital of Patras, Greece

*Corresponding author: Nikolaos Andreas Chrysanthakopoulos, Oncologist, Specialized in Clinical Oncology, Cytology and Histopathology, Department of Pathological Anatomy, Medical School, University of Athens, Athens, Greece, Tel: 0030-2610-225288, E-mail: [email protected], [email protected]

Received Date: November 7, 2022

Publication Date: December 14, 2022

Citation: Chrysanthakopoulos NA, et al. (2022). Assessment of Periodontal Disease Indices in Breast Cancer Patients: A Case-Control Study. Cases. 1(1):6.

Copyright: Chrysanthakopoulos NA, et al. © (2022).

ABSTRACT

Background/Aim: Breast cancer is the most prevalent malignant tumor and the leading cause of cancer in females in Europe. The purpose of the current research was to assess the potent discrepancies concerning the periodontal health status between females suffering from invasive ductal and lobular carcinoma, confirmed by histopathological examinations, and healthy ones. Materials and Methods: Data from an oral and dental clinical examination of 130 females suffering from breast cancer and 290 matching healthy controls were collected through a modified standardized questionnaire and analyzed using a univariate and multivariate regression model. Periodontal status concerned the following indices, Gingival Index (GI), Probing Pocket Depth (PPD), Clinical Attachment Loss (CAL), and Bleeding on Probing (BOP). Odds ratios (OR’s) and 95% Confidence Intervals (CI’s) were also recorded after adjustment for potential con-founders. Results: Female breast cancer patients showed worst CAL compared with healthy females (p=0.040, OR=1.787, 95% CI=1.208-2.651) after controlling for smoking and socio-economic level. Conclusion: CAL was statistically significantly different between females who were suffered from breast cancer and healthy ones.

Keywords: Breast Cancer, Periodontal disease, Risk factors, Females