The Effect of Treprostinil on Metabolic Profile in a Patient with Secondary Pulmonary Hypertension from Chronic Lung Disease

¹Division of Pediatric Intensive Care Unit, Department of Pediatrics, Morgan Stanley Children’s Hospital of New York-Presbyterian, Columbia University Medical Center, New York, New York, USA

²Pediatric Nutrition Support Specialist, New York-Presbyterian/Morgan Stanley Children's Hospital, New York, New York, USA

Received Date: May 16, 2023

Publication Date: June 12, 2023

Citation: Ravindranath Thyyar M, et al. (2023). The Effect of Treprostinil on Metabolic Profile in a Patient with Secondary Pulmonary Hypertension from Chronic Lung Disease. Cases. 2(2):12.

Copyright: Ravindranath TM, et al. © (2023)

*Corresponding Author: Thyyar M. Ravindranath, MD, Division of Pediatric Intensive Care Unit, Department of Pediatrics, Morgan Stanley Children’s Hospital of New York-Presbyterian, Columbia University Medical Center, New York, New York, USA; E-mail: [email protected]

ABSTRACT

The effects of medications used in the Pediatric Intensive Care Unit (PICU) on resting energy expenditure (REE) are not well known. Studying the effects of medication on REE would help to tailor energy needs of critically ill children more precisely. The use of Indirect Calorimeter (IC) has helped to measure REE accurately in critically ill patients. We describe the effect of continuous infusion of prostaglandin, treprostinil on REE and other parameters measured by IC in a child with pulmonary hypertension secondary to chronic lung disease and giant omphalocele. It appears that the effects of treprostinil on parameters measured by IC were dose dependent. This case report illustrates the importance of accurately measuring REE to modify nutritional therapy in critically ill children in PICU.

Keywords: Pediatric Intensive Care Unit, Resting Energy Expenditure, Indirect Calorimeter, Pulmonary Hypertension, Treprostinil, Chronic Lung Disease